Physiological Activity of Docosahexaenoic Acid
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چکیده
منابع مشابه
In silico Screening and Evaluation of the Anticonvulsant Activity of Docosahexaenoic Acid-Like Molecules in Experimental Models of Seizures
Background: Resistance to antiepileptic drugs as well as intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid (DHA), make it as a good candidate for designing and development of the new anticonvulsant medications. Methods: Ten DHA-based...
متن کاملDocosahexaenoic Acid (DHA)
Handling & Preparation Instructions This purified fatty acid is liquid at room temperature (oil) and not soluble in water. The product is supplied sterile. It can be solubilized in undiluted serum, ethanol or DMSO. The solubility of Docosahexaenoic acid in ethanol is at least 100 mg/ml. Docosahexaenoic acid has a solubility of 1 mg/ml in a solution of 0.15 M Tris-HCL (pH 8.5). We strongly recom...
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Introduction Docosahexaenoic acid (DHA) is an omega-3 fatty acid that falls into the larger category of polyunsaturated fatty acids (PUFAs). Although many chronic conditions are associated with excessive intake of dietary saturated and trans fatty acids (including obesity, insulin resistance, coronary heart disease, and some forms of cancer), research shows omega-3 fatty acids, including DHA, a...
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The effect of supplementation with the omega 3 polyunsaturated fatty acid (n-3 PUFA) docosahexaenoic acid (DHA) on membrane composition and amyloid-β1−42 (Aβ42) secretion was studied in human amyloid-β protein precursor-transfected Chinese Hamster Ovary (CHO) cells. Twenty-four hour incubation with a range of DHA concentrations resulted in a dosedependent increase in membrane DHA and eicosapent...
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Recently in PNAS, Hoshi et al. (1) report the results of elegant studies defining the molecular basis for the blood pressure-lowering effect of omega-3 fatty acids, in particular docosahexaenoic acid (DHA). They found that DHA, when infused intravenously, activated the large-conductance Caand voltage-activated K (BK) channels in vascular smooth muscle but that the infusion of DHA ethyl esters (...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1991
ISSN: 1884-2003
DOI: 10.5650/jos1956.40.974